The scientific questions of this axis are based on the problem of molecular interactions between the parasite and the host which has notably enabled our unit to be strongly involved in vaccine research against the complications of malaria. Understanding the molecular mechanisms involved in these interactions will help to develop optimal vaccine approaches and to understand the factors that can influence the response of populations to these vaccines. To do this, the characterization of parasites, the study of host factors, in particular the immune response, and certain plasma biomarkers of severity will be addressed.

Our experience and presence in the field also allow the study of the determinants of the encounter between the host and the pathogen by taking into account the environment, which can lead to the identification of new targets of therapeutic interest. The environment as such is not an object of study. However, in the case of infectious diseases, taking into account the environment close to individuals (village, dwelling, etc.) and behaviors (use of mosquito nets, taking treatment against the pathologies studied, daily activities, etc.) is essential to measure the risk of contact with the pathogen and therefore correctly assess and target prevention and control measures.

To study this dynamic, four themes, centered on infections, are developed: (1) infections in pregnant women; (2) infections in children and non-immune adults in tropical environments (3) vaccine development and therapeutic approaches and (4) pathogen reservoir and exposure risk measurement.

Finally, the thematic opening towards non-communicable diseases in connection with pollutants and global warming also finds its place in this thematic axis through epidemiological studies and adapted biostatistical approaches.

Responsible

gwladys

Gwladys BERTIN

HOPE Manager, Research Engineer, Prevention Assistant
Paris, Faculty of Pharmacy
Gilles COTTRELL

Gilles COTTRELL

Head of HOPE, Research Officer
Paris, Faculty of Pharmacy

Projects

Selection
  • All
  • Theme 1: Vaccine development and therapeutic approaches (2)
  • Topic 2: Infections in pregnant women (2)
  • Theme 3: Infections in children and non-immune adults in tropical environments (8)
  • Theme 4: Pathogen reservoir and exposure risk measurement (1)

Responsible

gwladys

Gwladys BERTIN

HOPE Manager, Research Engineer, Prevention Assistant
Paris, Faculty of Pharmacy
Gilles COTTRELL

Gilles COTTRELL

Head of HOPE, Research Officer
Paris, Faculty of Pharmacy

UMR Merit teams

Nicolas ARGY

Nicolas ARGY

University lecturer-hospital practitioner
Paris, Faculty of Pharmacy
Justine Bailly

Justine Bailly

Study engineer
Paris, Faculty of Pharmacy
Florence August 05, 2021

Florence BODEAU-LIVINEC

School of Advanced Studies in Public Health (EHESP)
Paris
Nadine-FIEVET

Nadine FIEVET

Researcher, Correspondent of Laboratoires Sud
Paris, Faculty of Pharmacy
Sayeh-GUEMOURI

Sayeh GUEMOURI

Research engineer, Lab manager
Paris, Faculty of Pharmacy
Adrian LUTY

Adrian LUTY

Research Director
Paris, Faculty of Pharmacy
Violeta

Violeta MOYA-ALVAREZ

In charge of research
Paris, Faculty of Pharmacy
Darius Sossou

Darius SOSSOU

PhD student
Accra, Benin, Ghana
Marie

Mary SUTER

Apprentice
Paris, Faculty of Pharmacy
Rachida-TAHAR

Rachida TAHAR

In charge of research
Paris, Faculty of Pharmacy
Nicaise-Tuikue-NDAM

Nicaise TUIKUE NDAM

Research Director
Accra, Benin
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Firmine VIWAMI

Study engineer
Paris, Faculty of Pharmacy
avatar man

Romeo ZOUMENOU

PhD student
Paris, Faculty of Pharmacy