2024

Theses defended: 

  • Darius Sossou, Dysfunction of regulatory T and B lymphocytes associated with the risk of neonatal sepsis.
  • Erasmes Gbaguidi, Consequences of HLA-G expression on immune response directed to P. Falciparum in young children.
  • Euripides Avokpaho, Study of risk factors for infection by soil-transmitted helminths in southern Benin.
  • Jeremy Fraering, Characterization of biological processes at the Host-Parasite interface by joint study of erythrocyte and plasma proteomes in the context of Plasmodium falciparum infection.
  • Lucille Hervé, Biochemical and structural characterization of the interactions of quinazoline derivatives with their potential targets in P. falciparum, with a view to optimizing molecules for antimalarial purposes.
  • Mariama Souffou, Toxoplasma gondii and Plasmodium falciparum: exploration of cross-reactivities for characterization of IgG specific to Toxoplasma in the context of congenital infection.
  • Romeo Zoumenou, Neurocognitive development of children from birth to ten years in Benin, Allada cohort.
  • Samuel Blankson, Study of the role of extracellular vesicles in the pathology of severe malaria.
  • Stephanie Bana Toko Mahame, Pharmaceutical representatives in Benin and their activities in the promotion and distribution of medicines: contributing to the study of the social construction of drug markets in Africa.
  • Valentin Joste, Study of the genetic diversity and clonality of Plasmodium ovale spp.

Theses in progress:

  • Abdoul-Omar Sick, Modulation of maternal and child monocytes in placental malaria.
  • Azza Bouzayene, Study of gametocytogenesis during bouts of Plasmodium falciparum malaria and their treatment.
  • Boris Zinsou, Spatial, genetic and epidemiological dynamics of plasmodium falciparum resistance to antimalarials in West Africa and the Sahel in the context of chemoprevention strategies.
  • Djelili Biaou, Identification of molecules involved in the immune tolerance mechanism.
  • Issiaka Babarimissa, Host-pathogen interaction contributing to the pathogenesis of severe malaria.
  • Ivan Svalko, Deep learning method for explainable and bias free classification of invisible phenotypes: application to a portable and sensitive diagnosis of malaria infection.
  • Ivy Bentil, A holistic approach to Schistosomiasis control: Elucidating the schistosome population structure, transmission dynamics, evolution and subsequent association to human immune response and morbidity.
  • Jean-Josue Tokpo, Search for genetic variants involved in simple forms of malaria by a multi-phenotype GWAS approach.
  • Océane Minka, Dynamics and determinants of asymptomatic carriage of malaria in Benin.

Other frameworks: 

  • Anna-Sica Guerard (M2)
  • Boris Zinsou (M2)
  • Brahim Benhamma (BTS)
  • Cecile Vernotte (M2 CISE)
  • Clara Guillou (M2)
  • Elisabeth Fadonougbo (M2)
  • Eole Durant-Simonnet (M2)
  • Eryann Bartel-Pessoa (BTS)
  • Jean-Josue Tokpo (M2)
  • Hawa Bachily (M1)
  • Ilona Thirion (BTS)
  • Lila Jaubert (L3)
  • Leopold Simon--Anglade (M2)
  • Marie Sutter (M1)
  • Maya Lachouri (M2)
  • Mary Ahouandjinou (BTS)
  • Mohamed Benzahi (M1)
  • Nana Salama Diawara (L3)
  • Paul Banto (M2)
  • Pema Christ (M2)
  • Quentin Goor (M2)
  • Romane Carole (L3)
  • Sandrine El Khoury (M2)
  • Sarah Anoma (M1)
  • Yanis Taybi (L3)
2023

Theses defended: 

  • Sebastien Dechavanne, Elucidate and circumvent immune tolerance to Malaria

Theses in progress:

  • Ayman Ztouti, Prospecting for new antimalarials for Artemisia spp. : bio-guided approach of "hits" compounds targeting chemo-refractory parasitic stages.
  • Azza Bouzaiene, Study of gametocytogenesis during bouts of Plasmodium falciparum malaria and their treatment.
  • Lucille Hervé, Biochemical and structural characterization of the interactions of quinazoline derivatives with their potential targets in P. falciparum, with a view to optimizing molecules for antimalarial purposes.
  • Jeremy Fraering, Characterization of biological processes at the Host-Parasite interface by joint study of erythrocyte and plasma proteomes in the context of Plasmodium falciparum infection.
  • Mahugnon Léger Erasmus Gbaguidi, Consequences of HLA-G expression on immune response directed to P. Falciparum in young children.
  • Valentin Joste, Study of the genetic diversity and clonality of Plasmodium ovale spp.
  • Mariama Souffou, Toxoplasma gondii and Plasmodium falciparum: exploration of cross-reactivities for characterization of IgG specific to Toxoplasma in the context of congenital infection.
  • Euripides Avokpaho, Study of risk factors for infection by soil-transmitted helminths in southern Benin.
  • Djelili Biaou, Identification of molecules involved in the immune rolerance mechanism.
  • Océane Minka, Dynamics and determinants of asymptomatic carriage of malaria in Benin.
  • Darius Sossou, Dysfunction of regulatory T and B lymphocytes associated with the risk of neonatal sepsis. 
  • Romeo Zoumenou, Neurocognitive development of children from birth to ten years in Benin, Allada cohort.

Other frameworks: 

  • Shilpa Vengatramane (3rd)
  • Brahim Benhamma (BTS)
  • Francine Ghislaine Toko Tchokoteu (M1)
  • Camille Arthur (M2)
  • Rodeline Telfils (M2)
  • Lina Boumediene (M2)
  • Yassine Louraoui (M2)
  • Iris Gomez (M2)
  • Georges El Khoury (M2)
  • Cecile Vernotte (M2 CISE)
  • Kabisha Sivakumaran (L1)
  • Theres Paramby (L3)
  • Imane Tabet (DFGSP3)
  • Camille Kepeklian (PUBLIC HEALTH DES)
  • Ines Besnard (FI 2nd year)
  • Djinn Bruand Petit (L3)
2022

Theses defended: 

  • Laurine Rondepierre, Biochemical study of the propeller domain of the protein PIK 13 involved in the resistance of plasmodium falciparum to arthemisinimates.
  • Tatiana Hountohotegbe, Immunogenicity of a vaccine candidate against pregnancy-associated malaria: cellular immune responses induced by the PAMVAC antigen during a phase LB trial.
  • Antoinette Keita, Search for new antimalarials targeting the hepatic phase of plasmodium falciparum: Study of simplified analogues in series of tazopsin.
  • Emilie Guillochon, Identification of conserved protein motifs with high vaccine potential within the PfEMP1 antigenic family associated with cerebral malaria.

Theses in progress:

  • Ayman Ztouti, Prospecting for new antimalarials for Artemisia spp. : bio-guided approach of "hits" compounds targeting chemo-refractory parasitic stages.
  • Azza Bouzaiene, Study of gametocytogenesis during bouts of Plasmodium falciparum malaria and their treatment.
  • Lucille Hervé, Biochemical and structural characterization of the interactions of quinazoline derivatives with their potential targets in P. falciparum, with a view to optimizing molecules for antimalarial purposes.
  • Jeremy Fraering, Characterization of biological processes at the Host-Parasite interface by joint study of erythrocyte and plasma proteomes in the context of Plasmodium falciparum infection.
  • Diana Roman, Identification of molecular targets of the antimalarial drug primaquine in the malaria agent Plasmodium falciparum.
  • Stephanie Mahame, Pharmaceutical representatives in Benin and their activities in promotion and distribution. Contribute to the study of the social construction of drug markets in Africa.
  • Mahugnon Léger Erasmus Gbaguidi, Consequences of HLA-G expression on immune response directed to P. Falciparum in young children.
  • Sebastien Dechavanne, Elucidate and circumvent immune tolerance to Malaria
  • Valentin Joste, Study of the genetic diversity and clonality of Plasmodium ovale spp.
  • Mariama Souffou, Toxoplasma gondii and Plasmodium falciparum: exploration of cross-reactivities for characterization of IgG specific to Toxoplasma in the context of congenital infection.
  • Euripides Avokpaho, Study of risk factors for infection by soil-transmitted helminths in southern Benin.

Other frameworks: 

  • Marie Verbeeck (BTS)
  • Remy Account (BTS)
  • Gregoire Perriguey (BTS)
  • Eugenie Baud (BTS)
  • Alejandro Rojaschaves (M2)
  • Deborah Matondo (M1)
  • Barbara Albero (M1)
  • Laila Aboutine (L3)
  • Faiza Talibi (L3)
  • Sara Shaik (L3)
  • Samet Karakulah (BTS)
  • Dan Tarcy (BTS)
  • Remi Dumas (L3)
  • Maxime Le Roux (BTS)
  • Quiterie Boyer-Vida (M1)
  • Hortense Marie Vistoire Pigasse (L2)
2021

Theses defended:

  • Sem Ezinmegnon, Effects of the regulation of TLRs in the neonatal immune response to Gram-negative infections in malaria-endemic areas.
  • Atikatou Mama, Adaptive evolution in Ghanaian Plasmodium falciparum isolates during Intermittent Preventive Treatment in Pregnancy - a genomic study.

Theses in progress: 

  • Lucille Hervé, Biochemical and structural characterization of the interactions of quinazoline derivatives with their potential targets in P. falciparum, with a view to optimizing molecules for antimalarial purposes.
  • Jeremy Fraering, Characterization of biological processes at the Host-Parasite interface by the joint study of erythrocyte and plasma proteomes in the context of infection with Plasmodium falciparum.
  • Laurine Rondepierre, Biochemical study of the propeller domain of the protein PIK 13 involved in the resistance of plasmodium falciparum to arthemisinimates.
  • Diana Roman, Identification of the molecular targets of the antimalarial drug primaquine in the malaria agent Plasmodium falciparum.
  • Antoinette Keita, Search for new antimalarials targeting the hepatic phase of plasmodium falciparum: study of simplified tazopsin serial analogues.
  • Stephanie Mahame, Pharmaceutical representatives in Benin and their activities in promotion and distribution. Contribute to the study of the social construction of drug markets in Africa.
  • Tatiana Hountohotegbe, Study of the immune responses induced by a vaccine against malaria associated with pregnancy.
  • Emilie GUILLOCHON, Identification of conserved protein motifs with high vaccine potential within the PfEMP1 antigenic family associated with cerebral malaria.
  • Abdou Khadre FALL, Targets and mechanisms of action of immunoglobulins G associated with protection against malaria.
  • Mahugnon Léger Erasmus GBAGUIDI, Consequences of HLA-G expression on immune response directed to P. Falciparum in young childre.
  • Sebastien DECHAVANNE, Elucidate and circumvent immune tolerance to Malaria.
  • Valentin JOSTE, Study of the genetic diversity and clonality of Plasmodium ovale spp.
  • Mariama SOUFFOU, Toxoplasma gondii and Plasmodium falciparum: exploration of cross-reactivities for characterization of IgG specific to Toxoplasma in the context of congenital infection.
  • Euripides AVOKPAHO, Study of risk factors for infection by soil-transmitted helminths in southern Benin.

Other frameworks:

  • Imtinane Ahmed-Fouatih (BTS)
  • Kevin Charlo (M2)
  • Lucille Herve (M2)
  • Sonia Nedjam (M1)
  • Ulcie Koty (M2)
  • Diariatou Diaby (M2)
  • Cloen Lhomme (M1)
  • Gueda Agne (L2)
  • Olfat Hamade (M2)
  • Justine Manso (L3)
  • Eugenie Baud (BTS)
  • Juliette Brochet (L3)
  • Lawrence Palazzo (DFGSP3)
  • Marine Gougeon (DFGSP3)
  • Gregoire Perriguey (BTS)
  • Agnes Gueda (L2)
2020

Theses defended:

  • Leonidas Tokplonou, Impact of Schistosoma haematobium infection on HLA-G expression, and on PF malaria and specific IgG response in children in the South.
  • Jacqueline Milet, Whole genome association study in cohorts of young children in Benin.
  • Cornelia Hounkonnou, Determinants of the dynamics of submicroscopic malaria infections during pregnancy, impact of control strategies and consequences on the health of mothers and newborns in Benin.
  • Edwige Apetoh, Therapeutic practices and consumption of pharmaceutical drugs in households in Cotonou, Benin: between low attendance of health structures and extensive use of informal circuits.

Theses in progress:

  • Laurine Rondepierre, Biochemical study of the propeller domain of the protein PIK 13 involved in the resistance of plasmodium falciparum to arthemisinimates.
  • Diana Roman, Identification of molecular targets of the antimalarial drug primaquine in the malaria agent Plasmodium falciparum.
  • Antoinette Keita, Search for new antimalarials targeting the hepatic phase of plasmodium falciparum: study of simplified tazopsin serial analogues.
  • Tatiana Hountohotegbe, Study of the immune responses induced by a vaccine against pregnancy-associated malaria.
  • Stephanie Mahame, Pharmaceutical representatives in Benin and their activities in promotion and distribution. Contribute to the study of the social construction of drug markets in Africa.
  • Sem Ezinmegnon, Effects of TLRs regulation in the neonatal immune response to Gram-negative infections in malaria-endemic areas.
  • Atikatou Mama, Adaptive evolution in Ghanaian Plasmodium falciparum isolates during Intermittent Preventive Treatment in Pregnancy - a genomic study.
  • Emilie Guillochon, Identification of conserved protein motifs with high vaccine potential within the PfEMP1 antigenic family associated with cerebral malaria.
  • Abdou Khadre FALL, Targets and mechanisms of action of immunoglobulins G associated with protection against malaria.
  • Mahugnon Léger Erasmus Gbaguidi, Consequences of HLA-G expression on immune response directed to P. Falciparum in young children.
  • Sebastien Dechavanne, Elucidating and circumventing the immune tolerance to Malaria.
  • Valentin Joste, Study of the genetic diversity and clonality of Plasmodium ovale spp.
  • Mariama Souffou, Toxoplasma gondii and Plasmodium falciparum: exploration of cross-reactivities for characterization of IgG specific to Toxoplasma in the context of congenital infection.
  • Euripides Avokpaho, Study of risk factors for infection by soil-transmitted helminths in southern Benin.

Other frameworks:

  • Anne-Emmanuelle Louis Joseph (BTS)
  • Clara Couto (BTS)
  • Eliot Murbach Studer (BTS)
  • Mathilde Patat (BTS)
  • Valentin Blin (BTS)
  • Abena Praba Prah (M1)
  • Anis Mansouri (M2)
  • Hajar Ahachad (M2)
  • William Boiledieu (M2)
2019

Theses defended:

  • Bernard Tornyigah, Malaria prevention in pregnancy: Challenges of Intermittent Preventive Treatment and Future Perspectives on Prevention Strategy.
  • Romain Coppee, Bioinformatics study of the PfK13 and PfCRT proteins involved in the resistance of plasmodium falciparum to antimalarial drugs.
  • Gino Agbota, Early maternal determinants of child health in the first months of life in Africa.
  • Jessica Pourraz, Regulating and producing drugs against malaria in Ghana and Benin: a matter of state? Pharmaceutical policies, quality standards and drug markets.
  • Margaux Chauvet, Study of the modulation by hemoglobin S of the presentation of plasmodial antigens on the erythrocyte surface and of the immune protection against malaria.

Theses in progress:

  • Laurine Rondepierre, Biochemical study of the propeller domain of the protein PIK 13 involved in the resistance of plasmodium falciparum to arthemisinimates.
  • Diana Roman, Identification of molecular targets of the antimalarial drug primaquine in the malaria agent Plasmodium falciparum.
  • Antoinette Keita, Search for new antimalarials targeting the hepatic phase of plasmodium falciparum: study of simplified tazopsin serial analogues.
  • Edwige Apetoh, Access to antimalarial treatments in Benin and Ghana: impact of health care systems on access to drugs for populations.
  • Jacqueline Milet, Whole genome association study in cohorts of young children in Benin.
  • Leonidas Tokplonou, Impact of Schistosoma haematobium infection on HLA-G expression, and on PF malaria and the specific IgG response in children in the south.
  • Tatiana Hountohotegbe, Study of the immune responses induced by a vaccine against pregnancy-associated malaria.
  • Sem EZINMEGNON, Effect of the regulation of TLRs in the neonatal immune response to Gram-negative infections in malaria-endemic areas.
  • Stephanie Mahame, Pharmaceutical representatives in Benin and their activities in promotion and distribution. Contribute to the study of the social construction of drug markets in Africa.
  • Atikatou MAMA Mama, Adaptive evolution in Ghanaian Plasmodium falciparum isolates during Intermittent Preventive Treatment in Pregnancy - a genomic study.
  • Cornelia HOUNKONNOU, Determination of the dynamics of submicroscopic malaria infections during pregnancy, impact of control strategies and consequences on the health of mothers and newborns in Benin.
  • Emilie GUILLOCHON, Identification of conserved protein motifs with high vaccine potential within the PfEMP1 antigenic family associated with cerebral malaria.
  • Abdou Khadre FALL, Targets and mechanisms of action of immunoglobulins G associated with protection against malaria.
  • Euripides AVOKPAHO, Study of risk factors for infection by soil-transmitted helminths in southern Benin.

Other frameworks:

  • Sami Guemouri (3rd discovery)
  • Paul Lesage (3rd discovery)
  • Lucille Breard (BTS)
  • Clara Couto (BTS)
  • Theana Fassier (BTS)
  • Abdou Khadre Fall (M2)
  • Lisa Casanas (DFGSP2)
  • Sabrine Hadji (BTS)
  • Marianne Lecat (DFGSP3)
  • Carine Berberi (M1)
  • Celina Mayinga (SUP'BIOTECH)
  • Aicha Hramch (M2)
  • Shona Gray - Switzman (M2)
  • Leslye Morel (BTS)
  • Valention Joste (M2)