BAObAB: Biocultural adaptation to malaria in Atacora, north Benin

This project aims to better understand the impact of the current and past lifestyle of human populations on the genetic and epigenetic adaptation to malaria and to clarify the role of human, parasitic and environmental factors on the variability of response to malaria infection. .

For this, we use a multidisciplinary approach integrating epidemiological genetics, population genetics, parasitology, immunology and socio-anthropology.

This integrative approach combining a detailed study of molecular, genetic or epigenetic mechanisms, and the explicit consideration of environmental, biotic and abiotic, but also socio-cultural factors, will make it possible to explore the determinants of human susceptibility to malaria.