DW3 is a multicenter clinical trial that includes sites in Benin, India and Malawi. The study is conducted in the same way, each site observing the same protocol.
The main objective is to demonstrate the possibility of interrupting the transmission of soil-transmitted helminths (Hookworms, Ascaris and Trichuris) using a community-wide mass treatment approach with albendazole (cTDM), every 6 months for 3 years. This is a randomized study in 40 clusters, each of 1 to 600 individuals, and which includes 4 arms, including an intervention arm (cTDM, 000 clusters), and a control arm (2 clusters) in which only school-aged children are treated with albendazole.
At the end of the study, analysis of stool samples by PCR will reveal whether the cTDM approach succeeded in reducing the prevalence of soil-transmitted helminths below the 2% threshold at which transmission is considered to have been interrupted.
Northern Partnership
- University of Washington,
- Seattle,
- WA,
- USA;
- LSHTM,
- London,
- England;
- Smith College,
- Northampton,
- MASS.
- USA;
- Quantigen LLC,
- Fishers IND,
- USA
Southern Partnership
- IRCB – CLIP,
- Calavi,
- Benign;
- CMC Vellore,
- Tamilnadu,
- India;
- Blantyre Institute for Community Outreach, Malawi;
Calendar
2021-2023
